Table 1 |
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|
Estimated Effects of Interventions (based on model of AMRA region) and assumed Compliance data that were inputted into POPMOD model. |
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|
Intervention |
Description |
Decrease in Incidence |
Decrease in Case-Fatality Rate |
Compliance |
|
|
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|
FOB1 |
Annual Fecal Occult Blood Testsa |
35.0% |
0% |
56.8% |
|
|
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|
FOB2 |
Biannual Fecal Occult Blood Testsa |
21.9% |
0% |
61.8% |
|
|
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|
SIG5 |
Sigmoidoscopy every 5 years[1]a |
38.9% |
0% |
45.0% |
|
|
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|
COL10 |
Colonoscopy every 10 yearsa |
52.6% |
0% |
45.0% |
|
|
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|
FOB1SIG5 |
Annual FOBT, SIG every 5 yearsa |
51.5% |
0% |
45.0% |
|
|
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|
FOB50 |
FOBT at age 50a |
2.6% |
0% |
71.8% |
|
|
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|
SIG50 |
Sigmoidoscopy at age 50a |
11.8% |
0% |
55.0% |
|
|
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|
COL50 |
Colonoscopy at age 50a |
25.9% |
0% |
55.0% |
|
|
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|
FOBSIG50 |
FOBT & SIG at age 50a |
13.2% |
0% |
55.0% |
|
|
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|
RX |
Medical Treatment of cancersb |
0% |
91.9% |
100% |
|
|
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|
FOB1RX |
Combination of FOB1 & RX |
35.0% |
17.9%c |
56.8% |
|
|
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|
FOB2RX |
Combination of FOB2 & RX |
21.9% |
12.9%c |
61.8% |
|
|
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|
SIG5RX |
Combination of SIG5 & RX |
38.9% |
3.4%c |
45.0% |
|
|
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|
COL10RX |
Combination of COL10 & RX |
52.6% |
3.9%c |
45.0% |
|
|
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|
FOB1SIG5RX |
Combination of FOB1SIG5 & RX |
51.5% |
18.3%c |
45.0% |
|
|
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|
FOB50RX |
Combination of FOB50 & RX |
2.6% |
0.5%c |
71.8% |
|
|
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|
SIG50RX |
Combination of SIG50& RX |
11.8% |
0.3%c |
55.0% |
|
|
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|
COL50RX |
Combination of COL50& RX |
25.9% |
0.4%c |
55.0% |
|
|
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|
FOBSIG50RX |
Combination of FOBSIG50 & RX |
13.2% |
0.5%c |
55.0% |
|
|
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|
FVCAMP |
Fruit & Vegetables campaign |
d) |
0% |
--- |
|
|
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|
FVCAMPRX |
Combination of FVCAMP & RX |
d) |
0%c |
--- |
|
|
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|
DRE1 |
Digital Rectal Exam annuallya |
17.6% |
0% |
50% |
|
|
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|
DRE1RX |
Combination of DRE1 & RX |
17.6% |
1.8%c |
50% |
|
|
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|
Notes: Subscripts 1,2,5,10 (eg: SIG5] in the intervention column denote the frequency of screening in years. Subscript 50, denotes a one off intervention at age 50. RX denotes the availabily of treatments for cancers in addition to the intervention program. Efficacy varied slightly between regions due to demographic differences. Efficacy considered on an age-sex specific basis. a) Denotes colonoscopy performed on all positive tests, with subsequent removal of lesions or polyps if discovered. b) Including surgical, radiotherapy and chemotherapy. c) In excess of decrease in CFR caused by treatment. d) Varies by region |
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|
Ginsberg et al. Cost Effectiveness and Resource Allocation 2010 8:2 doi:10.1186/1478-7547-8-2 |
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