Table 2

Estimation of initial distribution of visual acuity for the model from MARINA data [2].

MARINA
Model

Visual acuity*
Number (%) of patients
Visual acuity (letters)
Proportion of patients



90
0%
20/40 or better
(≥ 70 letters)
99 (13.8%)
75
14%
Better than 20/200 but worse than 20/40
(>35 but < 70 letters)*
519 (72.5%)
60
36%


45
36%
20/200 or worse (≤ 35 letters)
98(13.7%)
30
14%

* The eligibility criteria for the trial required patients to have a best corrected visual acuity of between 20/40 (70 letters) and 20/320 (25 letters).

Data from the three treatment arms were pooled.

‡ Half the patients in this visual acuity group were assigned to the 60 letter state in the Model and half were assigned to the 45 letter state.

Hurley et al. Cost Effectiveness and Resource Allocation 2008 6:12   doi:10.1186/1478-7547-6-12

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