Table 5 |
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|
Mean life time health outcomes, costs and average and incremental cost-effectiveness ratios (CERs) for the drug combinations in a scenario with very high CV risk. Incremental CERs are in addition reported for the high, medium and low CV risk scenarios. 95% confidence intervals are reported in brackets for the ICERs. |
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|
Very high CV risk |
Incremental CERs (USD/DALY) |
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|
|
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|
Intervention |
Life years saved (nominal) |
Costs |
DALYs |
ACER (USD/DALY) |
ICER (USD/DALY) |
High risk |
Medium risk |
Low risk |
|
|
||||||||
|
Asa |
1.6 |
138 |
0.8 |
163 |
(Dominated) |
|||
|
DiuVhigh |
1.6 |
74 |
0.9 |
85 |
85 (61 – 133) |
135 (95 – 212) |
149 (105 – 230) |
232 (163 – 266) |
|
Bet |
0.6 |
107 |
0.3 |
329 |
(Dominated) |
|||
|
Cab |
0.7 |
444 |
0.4 |
1095 |
(Dominated) |
|||
|
Sta |
2.7 |
882 |
1.6 |
540 |
(Dominated) |
|||
|
AsaDiu |
3.1 |
175 |
1.6 |
111 |
143 (108 – 197) |
222 (146 – 314) |
242 (182 – 337) |
377 (280 – 530) |
|
AsaBet |
2.2 |
208 |
1.1 |
182 |
(Dominated) |
|||
|
DiuBet |
2.2 |
141 |
1.1 |
124 |
(Dominated) |
|||
|
AsaDiuBet |
3.6 |
250 |
1.8 |
138 |
317 (169 – 3900) |
532 (265 – *) |
601 (305 – *) |
1009 (465 – *) |
|
AsaDiuSta |
4.9 |
1123 |
2.6 |
431 |
(Dominated) |
|||
|
DiuBetSta |
4.6 |
1086 |
2.5 |
433 |
(Dominated) |
|||
|
AsaBetSta |
4.4 |
1143 |
2.4 |
481 |
(Dominated) |
|||
|
AsaDiuBetSta |
5.4 |
1229 |
2.8 |
440 |
999 (752 – 1376) |
1588 (1175–2190) |
1739 (1270–2420) |
2749 (2010–3850) |
|
Poly |
6.3 |
1755 |
3.2 |
557 |
1476 (545–8000) |
2466 (856–16800) |
2735 (932–19500) |
4589 (1450–51000) |
|
|
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|
* > 100 000 |
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|
Robberstad et al. Cost Effectiveness and Resource Allocation 2007 5:3 doi:10.1186/1478-7547-5-3 |
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