Table 3

Health benefits and costs for metformin and the combination of metformin with nateglinide


Metformin
Combination
Difference

Cumulative cost (mean per patient)



     Complications
£3,548
£3,084
£-464
     Total
£5,093
£7,159
£2,066
Survival (mean, years)



     Life years (discounted)
13.5 (11.7)
13.9 (12.1)
0.39 (0.32)
     Quality Adjusted (discounted)
12.2 (10.7)
12.6 (11.0)
0.46 (0.37)
Cost-effectiveness



     Cost per LYG (discounted LYG)


£5,403 (6,772)
     Cost per QALY (discounted QALY)


£4,500 (5,609)

LYG = Life Year Gained QALY = Quality Adjusted Life Year

Ward et al. Cost Effectiveness and Resource Allocation 2004 2:2   doi:10.1186/1478-7547-2-2

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